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The myristylation signal of p60v-src functionally complements the N-terminal fps-specific region of P130gag-fps.

The P130gag-fps protein-tyrosine kinase of Fujinami sarcoma virus contains an N-terminal fps-specific domain (Nfps) that is important for oncogenicity. The N-terminal 14 amino acids of p60v-src, which direct myristylation and membrane association, can replace the gag-Nfps sequences of P130gag-fps (r...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Autores principales: Brooks-Wilson, A R, Ball, E, Pawson, T
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 1989
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363016/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2747647/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.5.2214-2219.1989
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