The myristylation signal of p60v-src functionally complements the N-terminal fps-specific region of P130gag-fps.

The P130gag-fps protein-tyrosine kinase of Fujinami sarcoma virus contains an N-terminal fps-specific domain (Nfps) that is important for oncogenicity. The N-terminal 14 amino acids of p60v-src, which direct myristylation and membrane association, can replace the gag-Nfps sequences of P130gag-fps (r...

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Bibliographic Details
Main Authors: Brooks-Wilson, A R, Ball, E, Pawson, T
Format: Artigo
Language:Inglês
Published: 1989
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC363016/
https://ncbi.nlm.nih.gov/pubmed/2747647
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