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A noncatalytic domain conserved among cytoplasmic protein-tyrosine kinases modifies the kinase function and transforming activity of Fujinami sarcoma virus P130gag-fps.

Proteins encoded by oncogenes such as v-fps/fes, v-src, v-yes, v-abl, and v-fgr are cytoplasmic protein tyrosine kinases which, unlike transmembrane receptors, are localized to the inside of the cell. These proteins possess two contiguous regions of sequence identity: a C-terminal catalytic domain o...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Sadowski, I, Stone, J C, Pawson, T
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367222/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3025655/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.12.4396
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