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Androgens Upregulate Cdc25C Protein by Inhibiting Its Proteasomal and Lysosomal Degradation Pathways

Cdc25C is a cell cycle protein of the dual specificity phosphatase family essential for activating the cdk1/Cyclin B1 complex in cells entering into mitosis. Since altered cell cycle is a hallmark of human cancers, we investigated androgen regulation of Cdc25C protein in human prostate cancer (PCa)...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Chou, Yu-Wei, Zhang, Li, Muniyan, Sakthivel, Ahmad, Humera, Kumar, Satyendra, Alam, Syed Mahfuzul, Lin, Ming-Fong
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630140/
https://ncbi.nlm.nih.gov/pubmed/23637932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061934
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