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Proteasomal and Lysosomal Protein Degradation and Heart Disease

In the cell, the proteasome and lysosomes represent the most important proteolytic machineries, responsible for the protein degradation in the ubiquitin-proteasome system (UPS) and autophagy, respectively. Both the UPS and autophagy are essential to protein quality and quantity control. Alterations...

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Detalhes bibliográficos
Main Authors: Wang, Xuejun, Robbins, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011941/
https://ncbi.nlm.nih.gov/pubmed/24239609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2013.11.006
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