Improved Antitumor Activity and Tumor Targeting of NH(2)-Terminal–Specific PEGylated Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand

Tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) is considered an attractive anticancer agent due to its tumor cell–specific cytotoxicity. However, its low stability, solubility, unexpected side effects, and weak pharmacokinetic profiles restrict its successful clinical application. T...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Chae, Su Young, Kim, Tae Hyung, Park, Kyeongsoon, Jin, Cheng-Hao, Son, Sohee, Lee, Seulki, Youn, Yu Seok, Kim, Kwangmeyung, Jo, Dong-Gyu, Kwon, Ick Chan, Chen, Xiaoyuan, Lee, Kang Choon
التنسيق: Artigo
اللغة:Inglês
منشور في: 2010
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629964/
https://ncbi.nlm.nih.gov/pubmed/20515949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-1076
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