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Identification of a Novel Arylsulfatase B Gene Mutation in Three Unrelated Iranian Mucopolysaccharidosis Type-VI Patients with Different Phenotype Severity

Background: Mucopolysaccharidosis type-VI (MPS-VI), which is inherited as an autosomal recessive trait, results from the deficiency of N-acetylgalactosamine 4-sulfatase (arylsulfatase B) activity and the lysosomal accumulation of dermatan sulfate. In this study, ARSB mutation analysis was performed...

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Détails bibliographiques
Auteurs principaux: Nouri, Nayerossadat, Nouri, Nargesossadat, Aryani, Omid, Kamalidehghan, Behnam, Houshm, Massoud
Format: Artigo
Langue:Inglês
Publié: Pasteur Institute of Iran 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629929/
https://ncbi.nlm.nih.gov/pubmed/23023219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6091/ibj.1049.2012
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