Aldose Reductase, Oxidative Stress and Diabetic Cardiovascular Complications

Cardiovascular disease represents the major cause of morbidity and mortality in patients with diabetes mellitus. Studies by us and others have implicated increased flux via aldose reductase (AR) as a key player in mediating diabetic complications, including cardiovascular complications. Data suggest...

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Autores principales: Vedantham, Srinivasan, Ananthakrishnan, Radha, Schmidt, Ann Marie, Ramasamy, Ravichandran
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629910/
https://ncbi.nlm.nih.gov/pubmed/22632267
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