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Thioredoxin-Interacting Protein Mediates Sustained VEGFR2 Signaling in Endothelial Cells required for Angiogenesis

OBJECTIVE: Thioredoxin-interacting protein (TXNIP) is an α-arrestin protein whose function is important for the regulation of vascular endothelial growth factor receptor 2 (VEGFR2) signaling and endothelial cell (EC) survival. Since VEGFR2 is critical for angiogenesis, we explored the role of TXNIP...

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Bibliografiska uppgifter
Huvudupphovsmän: Park, Shin-Young, Shi, Xi, Pang, Jinjiang, Yan, Chen, Berk, Bradford C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629821/
https://ncbi.nlm.nih.gov/pubmed/23393387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300386
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