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Fluid shear stress inhibits vascular inflammation by decreasing thioredoxin-interacting protein in endothelial cells
Regions in the vasculature that are exposed to steady laminar blood flow are protected from atherosclerosis as compared with regions where flow is disturbed. We found that flow decreased TNF-mediated VCAM1 expression by inhibiting JNK and p38. JNK inhibition correlated with inhibition of apoptosis s...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Clinical Investigation
2005
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC546457/ https://ncbi.nlm.nih.gov/pubmed/15696199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200523001 |
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