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Modification of the Catalytic Function of Human Hydroxysteroid Sulfotransferase hSULT2A1 by Formation of Disulfide Bonds

The human cytosolic sulfotransferase hSULT2A1 catalyzes the sulfation of a broad range of xenobiotics, as well as endogenous hydroxysteroids and bile acids. Reversible modulation of the catalytic activity of this enzyme could play important roles in its physiologic functions. Whereas other mammalian...

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Main Authors: Qin, Xiaoyan, Teesch, Lynn M., Duffel, Michael W.
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society for Pharmacology and Experimental Therapeutics 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629806/
https://ncbi.nlm.nih.gov/pubmed/23444386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.112.050534
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