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Metabolism of Beclomethasone Dipropionate by Cytochrome P450 3A Enzymes

Inhaled glucocorticoids, such as beclomethasone dipropionate (BDP), are the mainstay treatment of asthma. However, ∼30% of patients exhibit little to no benefit from treatment. It has been postulated that glucocorticoid resistance, or insensitivity, is attributable to individual differences in gluco...

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Autors principals: Roberts, Jessica K., Moore, Chad D., Ward, Robert M., Yost, Garold S., Reilly, Christopher A.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629798/
https://ncbi.nlm.nih.gov/pubmed/23512537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.202556
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