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Metabolic Pathways of Inhaled Glucocorticoids by the CYP3A Enzymes

Asthma is one of the most prevalent diseases in the world, for which the mainstay treatment has been inhaled glucocorticoids (GCs). Despite the widespread use of these drugs, approximately 30% of asthma sufferers exhibit some degree of steroid insensitivity or are refractory to inhaled GCs. One hypo...

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Библиографические подробности
Главные авторы: Moore, Chad D., Roberts, Jessica K., Orton, Christopher R., Murai, Takahiro, Fidler, Trevor P., Reilly, Christopher A., Ward, Robert M., Yost, Garold S.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Pharmacology and Experimental Therapeutics 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558858/
https://ncbi.nlm.nih.gov/pubmed/23143891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.112.046318
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