Targeting endothelial CD146 attenuates neuroinflammation by limiting lymphocyte extravasation to the CNS

The ability to selectively block the entry of leukocytes into the central nervous system (CNS) without compromising the immune system is an attractive therapeutic approach for treating multiple sclerosis (MS). Using endothelial CD146-deficienct mice as a MS model, we found that endothelial CD146 pla...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Duan, Hongxia, Xing, Shu, Luo, Yongting, Feng, Liqun, Gramaglia, Irene, Zhang, Ying, Lu, Di, Zeng, Qiqun, Fan, Kelong, Feng, Jing, Yang, Dongling, Qin, Zhihai, Couraud, Pierre-Olivier, Romero, Ignacio A., Weksler, Babette, Yan, Xiyun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629416/
https://ncbi.nlm.nih.gov/pubmed/23595028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01687
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