Targeting endothelial CD146 attenuates neuroinflammation by limiting lymphocyte extravasation to the CNS

The ability to selectively block the entry of leukocytes into the central nervous system (CNS) without compromising the immune system is an attractive therapeutic approach for treating multiple sclerosis (MS). Using endothelial CD146-deficienct mice as a MS model, we found that endothelial CD146 pla...

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Detaylı Bibliyografya
Asıl Yazarlar: Duan, Hongxia, Xing, Shu, Luo, Yongting, Feng, Liqun, Gramaglia, Irene, Zhang, Ying, Lu, Di, Zeng, Qiqun, Fan, Kelong, Feng, Jing, Yang, Dongling, Qin, Zhihai, Couraud, Pierre-Olivier, Romero, Ignacio A., Weksler, Babette, Yan, Xiyun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629416/
https://ncbi.nlm.nih.gov/pubmed/23595028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01687
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