Protease-sensitive prions with 144-bp insertion mutations

Insertion of 144-base pair (bp) containing six extra octapeptide repeats between residues 51 and 91 of prion protein (PrP) gene is associated with inherited prion diseases. Most cases linked to this insertion examined by Western blotting showed detectable proteinase K-resistant PrP(Sc) (rPrP(Sc)) re...

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Main Authors: Xiao, Xiangzhu, Cali, Ignazio, Dong, Zhiqian, Puoti, Gianfranco, Yuan, Jue, Qing, Liuting, Wang, Heming, Kong, Qingzhong, Gambetti, Pierluigi, Zou, Wen-Quan
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2013
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Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629288/
https://ncbi.nlm.nih.gov/pubmed/23515139
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