Protease-sensitive prions with 144-bp insertion mutations

Insertion of 144-base pair (bp) containing six extra octapeptide repeats between residues 51 and 91 of prion protein (PrP) gene is associated with inherited prion diseases. Most cases linked to this insertion examined by Western blotting showed detectable proteinase K-resistant PrP(Sc) (rPrP(Sc)) re...

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Detalhes bibliográficos
Main Authors: Xiao, Xiangzhu, Cali, Ignazio, Dong, Zhiqian, Puoti, Gianfranco, Yuan, Jue, Qing, Liuting, Wang, Heming, Kong, Qingzhong, Gambetti, Pierluigi, Zou, Wen-Quan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629288/
https://ncbi.nlm.nih.gov/pubmed/23515139
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