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Small antibody fusion proteins with complementarity-determining regions and lidamycin for tumor targeting therapy

Gelatinases are overexpressed in several types of maligancies and tumor stromal cells. Lidamycin is an enediyne antitumor antibiotic, which is composed of an apoprotein (LDP) and an active chromophore (AE). It is known that the heavy-chain complementarity-determining region-3 (CDR3) domain of scFv i...

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מידע ביבליוגרפי
Main Authors: ZHONG, GEN-SHEN, WU, MIN-NA, GUO, XIAO-FANG, XU, ZHI-SHAN, ZHANG, SHENG-HUA, ZHEN, YONG-SU
פורמט: Artigo
שפה:Inglês
יצא לאור: D.A. Spandidos 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629231/
https://ncbi.nlm.nih.gov/pubmed/23599760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2013.1143
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