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Chloroquine potentiates the anti-cancer effect of lidamycin on non-small cell lung cancer cells in vitro

AIM: To assess the synergistic actions of lidamycin (LDM) and chloroquine (CQ), a lysosomal enzyme inhibitor, in human non-small cell lung cancer (NSCLC) cells, and to elucidate the potential mechanisms. METHODS: Human NSCLC cell lines A549 and H460 were treated with CQ and/or LDM. Cell proliferatio...

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Publicat a:Acta Pharmacol Sin
Autors principals: Liu, Fang, Shang, Yue, Chen, Shu-zhen
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814038/
https://ncbi.nlm.nih.gov/pubmed/24727941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.3
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