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Identification of Human Monoclonal Antibodies Specific for Human SOD1 Recognizing Distinct Epitopes and Forms of SOD1

Mutations in the gene encoding human SOD1 (hSOD1) can cause amyotrophic lateral sclerosis (ALS) yet the mechanism by which mutant SOD1 can induce ALS is not fully understood. There is currently no cure for ALS or treatment that significantly reduces symptoms or progression. To develop tools to under...

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Bibliographische Detailangaben
Hauptverfasser: Broering, Teresa J., Wang, Hongyan, Boatright, Naomi K., Wang, Yang, Baptista, Katherine, Shayan, Gilda, Garrity, Kerry A., Kayatekin, Can, Bosco, Daryl A., Matthews, C. Robert, Ambrosino, Donna M., Xu, Zuoshang, Babcock, Gregory J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629177/
https://ncbi.nlm.nih.gov/pubmed/23613814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061210
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