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Friction-Limited Folding of Disulfide-Reduced Monomeric SOD1

The folding reaction of a stable monomeric variant of Cu/Zn superoxide dismutase (mSOD1), an enzyme responsible for the conversion of superoxide free radicals into hydrogen peroxide and oxygen, is known to be among the slowest folding processes that adhere to two-state behavior. The long lifetime, ∼...

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Bibliographic Details
Published in:Biophys J
Main Authors: Cohen, Noah R., Kayatekin, Can, Zitzewitz, Jill A., Bilsel, Osman, Matthews, C.R.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175461/
https://ncbi.nlm.nih.gov/pubmed/32191862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.02.028
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