Identification and Characterization of Broadly Neutralizing Human Monoclonal Antibodies Directed against the E2 Envelope Glycoprotein of Hepatitis C Virus

Nearly all livers transplanted into hepatitis C virus (HCV)-positive patients become infected with HCV, and 10 to 25% of reinfected livers develop cirrhosis within 5 years. Neutralizing monoclonal antibody could be an effective therapy for the prevention of infection in a transplant setting. To purs...

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Main Authors: Broering, Teresa J., Garrity, Kerry A., Boatright, Naomi K., Sloan, Susan E., Sandor, Frantisek, Thomas, William D., Szabo, Gyongyi, Finberg, Robert W., Ambrosino, Donna M., Babcock, Gregory J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786766/
https://ncbi.nlm.nih.gov/pubmed/19759151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01138-09
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