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A uridylate tract mediates efficient heterogeneous nuclear ribonucleoprotein C protein-RNA cross-linking and functionally substitutes for the downstream element of the polyadenylation signal.

Every RNA added to an in vitro polyadenylation extract became stably associated with both the heterogeneous nuclear ribonucleoprotein (hnRNP) A and C proteins, as assayed by immunoprecipitation analysis using specific monoclonal antibodies. UV-cross-linking analysis, however, which assays the specif...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Main Authors: Wilusz, J, Shenk, T
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1990
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362916/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1701018/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.12.6397
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