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Cleavage site determinants in the mammalian polyadenylation signal.

Using a series of position and nucleotide variants of the SV40 late polyadenylation signal we have demonstrated that three sequence elements determine the precise site of 3-end cleavage in mammalian pre-mRNAs: an upstream AAUAAA element, a down-stream U-rich element consisting of five nucleotides, a...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Chen, F, MacDonald, C C, Wilusz, J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1995
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307082/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7651822/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.14.2614
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