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Cleavage site determinants in the mammalian polyadenylation signal.

Using a series of position and nucleotide variants of the SV40 late polyadenylation signal we have demonstrated that three sequence elements determine the precise site of 3-end cleavage in mammalian pre-mRNAs: an upstream AAUAAA element, a down-stream U-rich element consisting of five nucleotides, a...

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Bibliografiska uppgifter
Huvudupphovsmän: Chen, F, MacDonald, C C, Wilusz, J
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1995
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC307082/
https://ncbi.nlm.nih.gov/pubmed/7651822
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