Partial deletion of alpha satellite DNA associated with reduced amounts of the centromere protein CENP-B in a mitotically stable human chromosome rearrangement.

A familial, constitutionally rearranged human chromosome 17 is deleted for much of the DNA in its centromeric region but retains full mitotic centromere activity. Fluorescence in situ hybridization, pulsed-field gel electrophoresis, and Southern blot analysis of the residual centromeric region revea...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Wevrick, R, Earnshaw, W C, Howard-Peebles, P N, Willard, H F
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1990
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362913/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2247061/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.12.6374-6380.1990
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