Partial deletion of alpha satellite DNA associated with reduced amounts of the centromere protein CENP-B in a mitotically stable human chromosome rearrangement.
A familial, constitutionally rearranged human chromosome 17 is deleted for much of the DNA in its centromeric region but retains full mitotic centromere activity. Fluorescence in situ hybridization, pulsed-field gel electrophoresis, and Southern blot analysis of the residual centromeric region revea...
Gespeichert in:
| Veröffentlicht in: | Mol Cell Biol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
1990
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362913/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2247061/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.12.6374-6380.1990 |
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