Sexually Dimorphic Effects of Catechol-O-Methyltransferase (COMT) Inhibition on Dopamine Metabolism in Multiple Brain Regions

The catechol-O-methyltransferase (COMT) enzyme metabolises catecholamines. COMT inhibitors are licensed for the adjunctive treatment of Parkinson's disease and are attractive therapeutic candidates for other neuropsychiatric conditions. COMT regulates dopamine levels in the prefrontal cortex (P...

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Main Authors: Laatikainen, Linda M., Sharp, Trevor, Harrison, Paul J., Tunbridge, Elizabeth M.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629045/
https://ncbi.nlm.nih.gov/pubmed/23613951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061839
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