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Sexually Dimorphic Effects of Catechol-O-Methyltransferase (COMT) Inhibition on Dopamine Metabolism in Multiple Brain Regions

The catechol-O-methyltransferase (COMT) enzyme metabolises catecholamines. COMT inhibitors are licensed for the adjunctive treatment of Parkinson's disease and are attractive therapeutic candidates for other neuropsychiatric conditions. COMT regulates dopamine levels in the prefrontal cortex (P...

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Hlavní autoři: Laatikainen, Linda M., Sharp, Trevor, Harrison, Paul J., Tunbridge, Elizabeth M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629045/
https://ncbi.nlm.nih.gov/pubmed/23613951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061839
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