Sexually Dimorphic Effects of Catechol-O-Methyltransferase (COMT) Inhibition on Dopamine Metabolism in Multiple Brain Regions

The catechol-O-methyltransferase (COMT) enzyme metabolises catecholamines. COMT inhibitors are licensed for the adjunctive treatment of Parkinson's disease and are attractive therapeutic candidates for other neuropsychiatric conditions. COMT regulates dopamine levels in the prefrontal cortex (P...

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Autores principales: Laatikainen, Linda M., Sharp, Trevor, Harrison, Paul J., Tunbridge, Elizabeth M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629045/
https://ncbi.nlm.nih.gov/pubmed/23613951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061839
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