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Deficiency in Mural Vascular Cells Coincides with Blood–Brain Barrier Disruption in Alzheimer's Disease

Neurovascular dysfunction contributes to Alzheimer's disease (AD). Cerebrovascular abnormalities and blood–brain barrier (BBB) damage have been shown in AD. The BBB dysfunction can lead to leakage of potentially neurotoxic plasma components in brain that may contribute to neuronal injury. Peric...

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Detalhes bibliográficos
Main Authors: Sengillo, Jesse D., Winkler, Ethan A., Walker, Corey T., Sullivan, John S., Johnson, Mahlon, Zlokovic, Berislav V.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628957/
https://ncbi.nlm.nih.gov/pubmed/23126372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12004
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