The Cytosolic Chaperonin CCT/TRiC and Cancer Cell Proliferation

The molecular chaperone CCT/TRiC plays a central role in maintaining cellular proteostasis as it mediates the folding of the major cytoskeletal proteins tubulins and actins. CCT/TRiC is also involved in the oncoprotein cyclin E, the Von Hippel-Lindau tumour suppressor protein, cyclin B and p21(ras)...

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Bibliographic Details
Main Authors: Boudiaf-Benmammar, Chafika, Cresteil, Thierry, Melki, Ronald
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628893/
https://ncbi.nlm.nih.gov/pubmed/23613750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060895
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