Prognostic Role of PIK3CA Mutation in Colorectal Cancer: Cohort Study and Literature Review

PURPOSE: Mutations in PIK3CA (the gene encoding the p110α catalytic subunit of phosphatidylinositide-3-kinase, PI3K) play an important role in colorectal carcinogenesis. Experimental evidence suggests that PIK3CA exon 9 and exon 20 mutations trigger different biological effects, and that concomitant...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Liao, Xiaoyun, Morikawa, Teppei, Lochhead, Paul, Imamura, Yu, Kuchiba, Aya, Yamauchi, Mai, Nosho, Katsuhiko, Qian, Zhi Rong, Nishihara, Reiko, Meyerhardt, Jeffrey A, Fuchs, Charles S, Ogino, Shuji
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628835/
https://ncbi.nlm.nih.gov/pubmed/22357840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-2410
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker