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Neoplastic transformation of mouse mammary epithelial cells by deregulated myc expression.

A spontaneously immortalized, nontumorigenic mouse mammary epithelial cell line (MMEC) was transfected with an activated myc construct by electroporation. Constitutive expression of myc in MMEC resulted in anchorage independence in soft agar and tumorigenicity in nude mice. The myc-expressing MMEC s...

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Détails bibliographiques
Publié dans:Cell Regul
Auteurs principaux: Telang, N T, Osborne, M P, Sweterlitsch, L A, Narayanan, R
Format: Artigo
Langue:Inglês
Publié: American Society for Cell Biology 1990
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362853/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2088530/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.1.11.863
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