Transforming c-Ki-ras mutation is a preneoplastic event in mouse mammary carcinogenesis induced in vitro by N-methyl-N-nitrosourea.

Mouse mammary epithelial cells can be transformed in primary cultures to preneoplastic and neoplastic states when treated with N-methyl-N-nitrosourea (MNU). Mammary carcinomas arising from MNU-induced hyperplastic alveolar nodules (a type of mouse mammary preneoplastic lesion) contained transforming...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Miyamoto, S, Sukumar, S, Guzman, R C, Osborn, R C, Nandi, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362264/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2181280/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.4.1593-1599.1990
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