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Neoplastic transformation of mouse mammary epithelial cells by deregulated myc expression.

A spontaneously immortalized, nontumorigenic mouse mammary epithelial cell line (MMEC) was transfected with an activated myc construct by electroporation. Constitutive expression of myc in MMEC resulted in anchorage independence in soft agar and tumorigenicity in nude mice. The myc-expressing MMEC s...

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Bibliografske podrobnosti
izdano v:Cell Regul
Principais autores: Telang, N T, Osborne, M P, Sweterlitsch, L A, Narayanan, R
Format: Artigo
Jezik:Inglês
Izdano: American Society for Cell Biology 1990
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362853/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2088530/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.1.11.863
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