Reprogramming of T Cells to Natural Killer–Like Cells upon Bcl11b Deletion

T cells develop in the thymus and are critical for adaptive immunity. Natural killer (NK) lymphocytes constitute an essential component of the innate immune system in tumor surveillance, reproduction and defense against microbes and viruses. Here we show that the transcription factor Bcl11b was expr...

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Autori principali: Li, Peng, Burke, Shannon, Wang, Juexuan, Chen, Xiongfeng, Ortiz, Mariaestela, Lee, Song-Choon, Lu, Dong, Campos, Lia, Goulding, David, Ng, Bee Ling, Dougan, Gordon, Huntly, Brian, Gottgens, Bertie, Jenkins, Nancy A., Copeland, Neal G., Colucci, Francesco, Liu, Pentao
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628452/
https://ncbi.nlm.nih.gov/pubmed/20538915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1188063
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