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Bcl11a is essential for lymphoid development and negatively regulates p53

Transcription factors play important roles in lymphopoiesis. We have previously demonstrated that Bcl11a is essential for normal lymphocyte development in the mouse embryo. We report here that, in the adult mouse, Bcl11a is expressed in most hematopoietic cells and is highly enriched in B cells, ear...

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Detalhes bibliográficos
Main Authors: Yu, Yong, Wang, Juexuan, Khaled, Walid, Burke, Shannon, Li, Peng, Chen, Xiongfeng, Yang, Wei, Jenkins, Nancy A., Copeland, Neal G., Zhang, Shujun, Liu, Pentao
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526365/
https://ncbi.nlm.nih.gov/pubmed/23230003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121846
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