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Bcl11a is essential for lymphoid development and negatively regulates p53

Transcription factors play important roles in lymphopoiesis. We have previously demonstrated that Bcl11a is essential for normal lymphocyte development in the mouse embryo. We report here that, in the adult mouse, Bcl11a is expressed in most hematopoietic cells and is highly enriched in B cells, ear...

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Bibliografiske detaljer
Main Authors: Yu, Yong, Wang, Juexuan, Khaled, Walid, Burke, Shannon, Li, Peng, Chen, Xiongfeng, Yang, Wei, Jenkins, Nancy A., Copeland, Neal G., Zhang, Shujun, Liu, Pentao
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526365/
https://ncbi.nlm.nih.gov/pubmed/23230003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121846
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