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Pernicious Attrition and Inter-RyR2 CICR Current Control in Cardiac Muscle

In cardiac muscle cells, ryanodine receptor (RyR) mediated Ca(2+) release from the sarcoplasmic reticulum (SR) drives the contractile apparatus. Spontaneous bouts of inter-RyR Ca(2+) induced Ca(2+) release (CICR) generate an elemental unit of SR Ca(2+) release called a spark. Sparks are localized ev...

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Bibliografiska uppgifter
Huvudupphovsmän: Gillespie, Dirk, Fill, Michael
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628281/
https://ncbi.nlm.nih.gov/pubmed/23369697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2013.01.011
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