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Dual actions of Meis1 inhibit erythroid progenitor development and sustain general hematopoietic cell proliferation
Myeloid ecotropic viral integration site 1 (Meis1) forms a heterodimer with Pbx1 that augments Hox-dependent gene expression and is associated with leukemogenesis and HSC self-renewal. Here we identified 2 independent actions of Meis1 in hematopoietic development: one regulating cellular proliferati...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society of Hematology
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3628121/ https://ncbi.nlm.nih.gov/pubmed/22665933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-01-403139 |
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