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Expanding probe repertoire and improving reproducibility in human genomic hybridization
Diagnostic DNA hybridization relies on probes composed of single copy (sc) genomic sequences. Sc sequences in probe design ensure high specificity and avoid cross-hybridization to other regions of the genome, which could lead to ambiguous results that are difficult to interpret. We examine how the d...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3627568/ https://ncbi.nlm.nih.gov/pubmed/23376933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt048 |
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