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Expanding probe repertoire and improving reproducibility in human genomic hybridization

Diagnostic DNA hybridization relies on probes composed of single copy (sc) genomic sequences. Sc sequences in probe design ensure high specificity and avoid cross-hybridization to other regions of the genome, which could lead to ambiguous results that are difficult to interpret. We examine how the d...

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Detalhes bibliográficos
Main Authors: Dorman, Stephanie N., Shirley, Ben C., Knoll, Joan H. M., Rogan, Peter K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627568/
https://ncbi.nlm.nih.gov/pubmed/23376933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt048
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