Ligand and protein kinase C downmodulate the colony-stimulating factor 1 receptor by independent mechanisms.

The turnover of the colony-stimulating factor 1 receptor (CSF-1R), the c-fms proto-oncogene product, is accelerated by ligand binding or by activators of protein kinase C (PKC), such as the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA). The mechanisms of ligand- and TPA-induced downmodula...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Downing, J R, Roussel, M F, Sherr, C J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1989
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362755/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2528680/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.7.2890-2896.1989
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