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VE-cadherin Signaling Induces EB3 Phosphorylation to Suppress Microtubule Growth and Assemble Adherens Junctions

Vascular Endothelial (VE)-cadherin homophilic adhesion controls endothelial barrier permeability through assembly of adherens junctions (AJs). We observed that loss of VE-cadherin-mediated adhesion induced the activation of Src and phospholipase C (PLC)γ2, which mediated Ca(2+) release from endoplas...

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Detalhes bibliográficos
Main Authors: Komarova, Yulia A., Huang, Fei, Geyer, Melissa, Daneshjou, Nazila, Garcia, Alexander, Idalino, Luiza, Kreutz, Barry, Mehta, Dolly, Malik, Asrar B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627495/
https://ncbi.nlm.nih.gov/pubmed/23159740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.10.011
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