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A bcr-v-abl oncogene induces lymphomas in transgenic mice.

In chronic myeloid leukemia and some cases of acute lymphoblastic leukemia, a 9;22 chromosome translocation has fused most of the c-abl oncogene to a gene designated bcr. To explore in vivo the biological effects of the chimeric gene, we introduced a facsimile of the translocation product, a bcr-v-a...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Hariharan, I K, Harris, A W, Crawford, M, Abud, H, Webb, E, Cory, S, Adams, J M
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1989
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362745/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2789335/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.7.2798-2805.1989
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