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Spiroaminal Model Systems of the Marineosins with Final Step Pyrrole Incorporation
In this Letter, we describe a short, 6-step enantioselective route to spiroaminal lactam model systems reminiscent of marineosins A and B has been developed starting from either (R)- or (S)-hydroxysuccinic acid, respectively, in ~9% overall yield. This route enables late stage incorporation of the p...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3627418/ https://ncbi.nlm.nih.gov/pubmed/23606772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2013.02.059 |
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