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Inhibitory Effects of Robo2 on Nephrin: A Crosstalk between Positive and Negative Signals Regulating Podocyte Structure

Robo2 is the cell surface receptor for the repulsive guidance cue Slit and is involved in axon guidance and neuronal migration. Nephrin is a podocyte slit-diaphragm protein that functions in the kidney glomerular filtration barrier. Here we report that Robo2 is expressed at the basal surface of mous...

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Detalhes bibliográficos
Main Authors: Fan, Xueping, Li, Qinggang, Pisarek-Horowitz, Anna, Rasouly, Hila Milo, Wang, Xiangling, Bonegio, Ramon G., Wang, Hang, McLaughlin, Margaret, Mangos, Steve, Kalluri, Raghu, Holzman, Lawrence B., Drummond, Iain A., Brown, Dennis, Salant, David J., Lu, Weining
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627357/
https://ncbi.nlm.nih.gov/pubmed/22840396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.06.002
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