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It cuts both ways: reconciling the dual roles of caspase-8 in cell death and survival

Caspase-8 can initiate apoptosis, but it is also required for embryonic development and immune cell proliferation. While several non-apoptotic roles for caspase-8 have been proposed, recent work has indicated that the requirement for caspase-8 in development and proliferation is defined by suppressi...

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Detalhes bibliográficos
Main Authors: Oberst, Andrew, Green, Douglas R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627210/
https://ncbi.nlm.nih.gov/pubmed/22016059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3214
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