A v-H-ras-dependent hemopoietic tumor model involving progression from a clonal stage of transformation competence to autocrine interleukin 3 production.

Autocrine interleukin 3 (IL-3)-secreting tumors were generated from an IL-3-dependent mouse mast cell line (PB-3c) after introduction of the v-H-ras oncogene. Tumor progression was characterized by four distinct phenotypes. The first corresponded to immortalized mast cells unresponsive to the oncoge...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Nair, A P, Diamantis, I D, Conscience, J F, Kindler, V, Hofer, P, Moroni, C
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1989
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362709/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2498644/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.3.1183-1190.1989
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