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Digital sorting of complex tissues for cell type-specific gene expression profiles

BACKGROUND: Cellular heterogeneity is present in almost all gene expression profiles. However, transcriptome analysis of tissue specimens often ignores the cellular heterogeneity present in these samples. Standard deconvolution algorithms require prior knowledge of the cell type frequencies within a...

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Detalhes bibliográficos
Main Authors: Zhong, Yi, Wan, Ying-Wooi, Pang, Kaifang, Chow, Lionel ML, Liu, Zhandong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626856/
https://ncbi.nlm.nih.gov/pubmed/23497278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-89
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