Molecular pathway identification using biological network-regularized logistic models

BACKGROUND: Selecting genes and pathways indicative of disease is a central problem in computational biology. This problem is especially challenging when parsing multi-dimensional genomic data. A number of tools, such as L(1)-norm based regularization and its extensions elastic net and fused lasso,...

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Autori principali: Zhang, Wen, Wan, Ying-wooi, Allen, Genevera I, Pang, Kaifang, Anderson, Matthew L, Liu, Zhandong
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046566/
https://ncbi.nlm.nih.gov/pubmed/24564637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-S8-S7
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