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Combinatorial therapy discovery using mixed integer linear programming

Motivation: Combinatorial therapies play increasingly important roles in combating complex diseases. Owing to the huge cost associated with experimental methods in identifying optimal drug combinations, computational approaches can provide a guide to limit the search space and reduce cost. However,...

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Detalhes bibliográficos
Main Authors: Pang, Kaifang, Wan, Ying-Wooi, Choi, William T., Donehower, Lawrence A., Sun, Jingchun, Pant, Dhruv, Liu, Zhandong
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016706/
https://ncbi.nlm.nih.gov/pubmed/24463180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu046
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