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Non-genotoxic anti-neoplastic effects of ellipticine derivative NSC176327 in p53-deficient human colon carcinoma cells involve stimulation of p73

We previously performed a high-throughput screen using real-time noninvasive bioluminescence imaging of p53 transcriptional activity and identified a group of small molecules that trigger p53-like transcriptional responses in p53-deficient tumor cells. Here we further examined the anti-tumor effects...

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Detalhes bibliográficos
Main Authors: Lu, Chao, Wang, Wenge, El-Deiry, Wafik S.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626664/
https://ncbi.nlm.nih.gov/pubmed/19106635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.7.12.7461
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